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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
17.88
Human Site:
S618
Identified Species:
39.33
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
S618
S
N
S
S
L
V
S
S
N
S
L
R
E
S
H
Chimpanzee
Pan troglodytes
XP_523109
766
83908
S733
S
N
S
S
L
V
S
S
N
S
L
R
E
S
H
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
N610
N
S
S
L
V
S
S
N
S
L
R
E
S
H
S
Dog
Lupus familis
XP_535524
651
71773
S618
S
N
S
S
L
V
S
S
N
S
L
R
E
S
H
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
S618
S
N
S
S
L
V
S
S
N
S
L
R
E
S
H
Rat
Rattus norvegicus
O70260
628
68345
I596
A
P
G
R
V
S
S
I
V
A
P
G
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
N717
N
G
S
S
S
G
S
N
S
S
L
V
S
S
N
Chicken
Gallus gallus
NP_001026627
564
62782
M532
D
Y
R
H
P
F
H
M
T
P
M
P
Y
D
L
Frog
Xenopus laevis
NP_001079161
649
71676
S617
G
S
N
S
S
L
V
S
S
N
S
L
R
E
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
T711
N
P
S
S
G
S
Q
T
P
T
S
Q
Y
G
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
P646
I
N
S
Y
N
E
D
P
H
S
I
A
G
G
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
13.3
N.A.
40
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
46.6
100
N.A.
100
33.3
N.A.
66.6
6.6
46.6
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
10
37
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
10
10
0
0
0
0
0
10
10
19
0
% G
% His:
0
0
0
10
0
0
10
0
10
0
0
0
0
10
37
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
37
10
0
0
0
10
46
10
0
0
19
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
28
46
10
0
10
0
0
19
37
10
0
0
0
0
10
% N
% Pro:
0
19
0
0
10
0
0
10
10
10
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
10
37
10
0
0
% R
% Ser:
37
19
73
64
19
28
64
46
28
55
19
0
28
55
28
% S
% Thr:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% T
% Val:
0
0
0
0
19
37
10
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
0
0
0
19
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _